Category | Report | Subject | Science |
---|---|---|---|
University | Coventry University (CU) | Module Title | 6039BMS Cancer Biology |
The aim of this analysis therefore is to evaluate the relevance of these variants in the progression for melanoma and reveal clinical strategies that can help in developing targeted therapies. This report provides a detailed analysis of four genomic variants—rs121913513 (KIT), COSV60188073 (HIF1A), rs778696237 (CDK4), and rs1057519985 (TP53)— from the standpoint of their possible effects on protein function, pathogenicity, and potential consequences for diagnosing and treating melanoma patients. Data are obtained from ClinVar, COSMIC, dbSNP and PubMed databases as well as relevant scientific articles.
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