Category | Assignment | Subject | Education |
---|---|---|---|
University | - | Module Title | Clinical Prediction Rule - CASP |
1. Is the CPR clearly defined?
HINT:
Yes, can’t tell no
2. The population from which the rule was derived included an appropriate spectrum of patients?
HINT: Consider
Yes, can’t tell no
3. Was the rule validated in a different group of patients?
HINT:
Yes, can’t tell no
Is it worth continuing?
4. Were the predictor variables and the Yes, Can’t tell outcome evaluated in a blinded fashion?
HINT: Did;
Yes, can’t tell no
5. Were the predictor variables and the outcome evaluated in the whole sample selected initially?
HINT:
Yes, can’t tell no
6. Are the statistical methods used to construct and validate the rule clearly described?
HINT:
Yes, can’t tell no
7. Can the performance of the rule be calculated?
HINT: Rule –
Outcome + | Outcome – | |
---|---|---|
Rule + | a | b |
Rule – | c | d |
Performance results can be presented as: Sens, Sp, + LR, -LR, ROC curve, calibration curves, etc
Sensitivity = a/(a+c)
Specificity = d/(b+d)
LR+ = sens/(1-sp)
LR- = (1-sens)/sp
Yes, can’t tell no
8. How precise was the estimate of the treatment effect?
Did they try to refine the rule with other variables to see whether the precision could be improved or the rule simplified?
HINT: Think about
Yes, can’t tell no
(C) Will the results help locally? / Are the findings applicable to the scenario?
9. Would the prediction rule be reliable and the results interpretable if used for your patient?
HINT: Consider
Yes, can’t tell no
10. Is the rule acceptable in your case?
HINT: Consider
Yes, can’t tell No
11. Would the results of the rule modify your decision about the management of the patient or the information you can give to him/her?
HINT: Consider
Yes, can’t tell No
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